How does loop of Henle interacts with furosemide (Lasix)?

- Furosemide works by acting to excrete sodium, potassium, and chloride in the ascending limb of the loop of Henle.

(this portion below is taken straight from the horse's mouth wikipedia)

In the kidney, the loop of Henle or Henle's loop is the portion of the nephron that leads from the proximal convoluted tubule to the distal convoluted tubule. The loop has a hairpin bend in the renal medulla. The main function of this structure is to reabsorb water and ions from the urine. To do this, it uses a countercurrent multiplier mechanism in the medulla. It is named after its discoverer, F. G. J. Henle.